CAR-T Intelligence — Foundation Learning Guide¶
For a reader with no background in this area. If you have watched the Foundations film series, this follows directly from it.
The one idea to hold¶
A chimeric antigen receptor is a designed protein that teaches a patient's own T-cells to recognise a target on cancer cells.
What this subject does with that idea¶
Reasons about engineered T-cell therapies — which construct, for which patient, with which risks.
CAR-T is powerful and dangerous in the same breath. Construct choice and its safety counterweight belong in the same conversation.
Decision support for a qualified clinician — never autonomous diagnosis or prescribing. Every output on this page is intended to inform a clinician's judgement, not replace it.
What it cannot do¶
On-target off-tumour toxicity and cytokine release are real. Any construct suggestion carries its monitoring requirement.
Stating the limit is not a disclaimer bolted on the end — it is how you tell a tool that helps from a tool that misleads.
Vocabulary you will meet¶
| Term | Plain meaning |
|---|---|
| Capability | One named thing the platform can do, registered in capabilities.json |
live / planned |
Whether a capability actually answers today, or is intended |
| Decision support | Output that informs a clinician; it never decides |
| LIVE / REPRESENTATIVE / BURST | Whether a demo ran now, was pre-computed, or ran on remote GPUs |
Try it¶
The demo for this subject is A1:
.venv/bin/python scripts/run_demo.py A1
If it reports BLOCKED, the message names exactly what is missing. That is intentional — a demo
that cannot run says so rather than showing you something canned.