Cardiology Engine¶
live Domain: clinical Type: engine
11 clinical workflows and 6 risk calculators spanning prevention, intervention, and rhythm; CAC + 10-year ASCVD prevention logic (ACC/AHA), handing to Pharmacogenomics for the genetically safe drug. Decision support.
A narrated, captioned explainer. Decision support for a qualified clinician.

Illustrative. Decision support for a qualified clinician — never autonomous diagnosis or prescribing.
In plain terms¶
The Cardiology Engine is a cardiovascular risk-and-prevention engine: 11 clinical workflows and 6 risk calculators spanning prevention, intervention, and rhythm. Its signature move is precision prevention — combine a coronary calcium score with the patient's genetics, then hand off to pharmacogenomics to pick the statin that is actually safe for them.
Why it matters¶
The highest-leverage cardiology happens before the heart attack. A calcium score plus a ten-year risk estimate tells you whether to treat; the patient's pharmacogenomics tells you which drug won't harm them. Doing both, together, is precision prevention rather than one-size-fits-all.
For a patient: prevention matched to their heart and their genes — the right risk assessment, then a drug that is safe for them specifically.
How it works¶

Coronary calcium and 10-year ASCVD risk, handed to pharmacogenomics for the safe drug. Illustrative.
- Ingest — imaging, genotype, and labs.
- Score — coronary artery calcium (CAC) and 10-year ASCVD risk, using the ACC/AHA prevention logic.
- Recommend — across 11 workflows and 6 calculators, from prevention through intervention to rhythm.
- Hand off — to the Pharmacogenomics Intelligence Agent for the genetically safe drug and dose.
What goes in, what comes out¶
- In: a query and the patient context (imaging, genotype, labs).
- Out: risk scores and prevention recommendations.
Where it fits¶

Calcium score to genetically safe statin: imaging in, pharmacogenomics out. Illustrative.
It joins the Clinical Imaging Engine (for the calcium score) and the Pharmacogenomics agent (for the safe drug) — the spine of the cross-modality prevention demonstration.
Honest limits¶
- Guideline-cited. The calculators implement published ACC/AHA logic and cite it.
- Decision support, not prescribing. Risk scores and recommendations support a clinician's decision; the engine never prescribes.
Interface¶
- Endpoint:
localhost:8126· Invoke path:/ - Serving: native · GPU: no · Cost class: —
Inputs
| Name | Shape | Semantic | Notes |
|---|---|---|---|
query |
scalar | — | |
patient_context |
map | patient_context |
Outputs
| Name | Shape | Semantic | Notes |
|---|---|---|---|
answer |
map | risk_scores |
Tags: engine · cardiology
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Note
Status and interface are generated from the capability registry (lib/hcls_common/capabilities.json) — the site cannot claim ahead of the code. All clinical output is decision support for a qualified clinician, never autonomous diagnosis.