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Neurology Intelligence Agent

Part of the Precision Intelligence Network — one of 11 specialized agents sharing a common molecular foundation within the HCLS AI Factory.

RAG-powered clinical decision support for neurology, covering 10 disease domains, 14 vector collections, 10 validated clinical scales, and 8 evidence-based workflows.

Key Capabilities

  • Acute Stroke Triage: NIHSS scoring, ASPECTS evaluation, tPA/thrombectomy eligibility (DAWN/DEFUSE-3)
  • Dementia Evaluation: MoCA screening, ATN biomarker staging, anti-amyloid therapy eligibility
  • Epilepsy Classification: ILAE 2017, 12 syndromes, drug-resistant epilepsy assessment, surgical candidacy
  • Brain Tumor Grading: WHO 2021 molecular classification (IDH, MGMT, 1p/19q)
  • MS Monitoring: EDSS scoring, NEDA-3 status, DMT escalation, JCV/PML risk
  • Parkinson's Assessment: MDS-UPDRS Part III, Hoehn-Yahr staging, DBS candidacy
  • Headache Classification: ICHD-3 criteria, HIT-6 scoring, CGRP therapy guidance
  • Neuromuscular Evaluation: ALSFRS-R scoring, EMG/NCS pattern analysis

Architecture

  • API: FastAPI on port 8528
  • UI: Streamlit on port 8529
  • Vector DB: Milvus 2.4 with 14 domain-specific collections (BGE-small 384-dim)
  • LLM: Claude (Anthropic) for evidence synthesis
  • Tests: 209 automated tests across 12 modules

Documentation

Document Description
Production Readiness Report 25-section PRR with full capability, data, and test inventory
Project Bible Architecture, directory structure, data models, quality gates
Architecture Guide System design, scale calculator architecture, stroke pipeline, ATN staging
White Paper Problem statement, RAG solution, clinical capabilities, results
Deployment Guide Docker standalone, integrated, local dev, configuration
Demo Guide 5 clinical scenarios: stroke, AD, epilepsy, tumor, MS
Learning Guide -- Foundations Brain anatomy, stroke, dementia, seizures, MS, scales
Learning Guide -- Advanced ATN, DAWN/DEFUSE-3, NEDA-3, EMG/NCS, DBS, surgery
Research Paper Technical research paper

Clinical Decision Support Disclaimer

This agent is a clinical decision support research tool. It is not FDA-cleared and is not intended as a standalone diagnostic device. All recommendations should be reviewed by qualified healthcare professionals. Apache 2.0 License.